AMACR 抗体
Quick Overview for AMACR 抗体 (ABIN6936404)
抗原
See all AMACR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes a protein of 42 kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human AMACR protein
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亚型
- IgG2b kappa
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anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibody
AMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1864 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1723 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 1-198) antibodyAMACR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人, 小鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 2A10F3 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351) antibodyAMACR 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 312-326) antibodyVerified AMACR 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibodyAMACR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rAMACR-1864 unconjugated Recombinant Antibody
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Monoclonal AMACR-2748R unconjugated Recombinant Antibody
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351), (C-Term) antibodyAMACR 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18736 unconjugated
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应用备注
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: PC3, HEK cells. Prostate Adenocarcinoma, Human Liver and and Kidney Tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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别名
- AMACR
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背景
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Alpha-methylacyl-CoA Racemase, CBAS4, Da1-8, Macr1, RACE, RM,AMACR / p504S (Prostate Cancer Marker)
Cellular localisation: Cytoplasmic -
分子量
- 42kDa
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基因ID
- 23600, 508343
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UniProt
- Q9UHK6
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途径
- Monocarboxylic Acid Catabolic Process
抗原
-
