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MUC1 抗体 (AA 1101-1255)

Name: MUC1 抗体 (AA 1101-1255)
SKU: ABIN687367
Availability: OutOfStock

MUC1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human breast cancer labeled with Anti-CA153/MUC1/KL-6 Polyclonal Antibody, Unconjugated (ABIN687367) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC

Formalin-fixed and paraffin embedded human breast cancer labeled with Anti-CA153/MUC1/KL-6 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining.

IHC (p)

2 images

(1 reference)

产品编号 ABIN687367

发货至: 中国

Datasheet as PDF

抗原 See all MUC1 抗体

MUC1 (Mucin 1 (MUC1))
抗原表位
26

19

16

15

12

8

7

6

6

5

5

5

5

4

4

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1101-1255
适用
270

57

29

12

6

5

4

4

2

2

2

2

1
人, 小鼠, 大鼠
宿主
196

87

2

1
兔
Compatible Secondaries
克隆类型
175

106

5
多克隆
标记
145

26

16

11

11

10

5

5

5

5

5

5

3

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1
This MUC1 antibody is un-conjugated
应用范围
139

136

102

83

75

47

26

24

24

19

18

13

13

12

6

6

6

4

3

2

2

2

2

2

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human MUC1

亚型

IgG

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MUC1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Mucin 1 (MUC1) (C-Term) antibody
MUC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 IHC, WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Taki, Ohmuraya, Tanji, Komatsu, Hashimoto, Semba, Araki, Kawaguchi, Baba, Furukawa: "GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm." in: Oncogene, Vol. 35, Issue 18, pp. 2407-12, (2016) (PubMed).
抗原

MUC1 (Mucin 1 (MUC1))

别名

MUC1 (MUC1 产品)

别名

CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody

背景

Synonyms: EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC, Mucin-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, Carcinoma-associated mucin, Episialin, Krebs von den Lungen-6, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin, MUC1
Background: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

基因ID

4582

UniProt

P15941

途径

Negative Regulation of intrinsic apoptotic Signaling