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ERBB3 抗体 (AA 661-760)

Name: ERBB3 抗体 (AA 661-760)
SKU: ABIN686767
Availability: OutOfStock

This anti-ERBB3 antibody is a 兔多克隆 antibody detecting ERBB3 in ELISA, IF (p), IF (cc), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 2+ publications.

Formalin-fixed and paraffin embedded rat brain labeled with Anti-ErbB-3/HER3 Polyclonal Antibody, Unconjugated (ABIN686767) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (ERBB3 抗体 (AA 661-760))

IHC

Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti-ErbB-3/HER3 Polyclonal Antibody, Unconjugated (ABIN686767) followed by conjugation to the secondary antibody and DAB staining (ERBB3 抗体 (AA 661-760))

IHC

2 images

(2 references)

产品编号 ABIN686767

发货至: 中国

Quick Overview for ERBB3 抗体 (AA 661-760) (ABIN686767)

抗原

See all ERBB3 抗体

ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This ERBB3 antibody is un-conjugated

应用范围

ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product ERBB3 Primary Antibody

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AA 661-760

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human ErbB-3

亚型

IgG
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 707-964) antibody
ERBB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55), (N-Term) antibody
ERBB3 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01467 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibody
ERBB3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-130) antibody
ERBB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibody
ERBB3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55) antibody
ERBB3 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1328) antibody
ERBB3 适用: 人, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 21-332) antibody
ERBB3 适用: 人 IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F12 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-131) antibody
ERBB3 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated

anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibody
Verified ERBB3 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

应用备注

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Cao, Chen, Chen, Xiong: "Positive prognostic value of HER2-HER3 co-expression and p-mTOR in gastric cancer patients." in: BMC cancer, Vol. 17, Issue 1, pp. 841, (2018) (PubMed).

Xiao, Pepe, Wang, Luo, Zhang, Zeng, Zhang, Hu, Ye, Xu: "Nrf3-Pla2g7 interaction plays an essential role in smooth muscle differentiation from stem cells." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 32, Issue 3, pp. 730-44, (2012) (PubMed).
抗原

ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

别名

ErbB-3/HER3

背景

Synonyms: HER3, LCCS2, ErbB-3, c-erbB3, erbB3-S, MDA-BF-1, c-erbB-3, p180-ErbB3, p45-sErbB3, p85-sErbB3, Receptor tyrosine-protein kinase erbB-3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, ERBB3
Background: The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain. It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation. However it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, bladder and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported but they have not been thoroughly characterized.

基因ID

2065

UniProt

P21860

途径

RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway