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CBP 抗体

This anti-CBP antibody is a 兔 多克隆 antibody detecting CBP in WB, IHC (p) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN685957
发货至: 中国

Quick Overview for CBP 抗体 (ABIN685957)

抗原

See all CBP (CREBBP) 抗体
CBP (CREBBP) (CREB Binding Protein (CREBBP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CBP

    亚型

    IgG
  • 应用备注

    WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CBP (CREBBP) (CREB Binding Protein (CREBBP))

    别名

    Cbp

    背景

    Synonyms: CREB-binding protein, CREBBP, GTF2D, TATA binding factor, TATA box factor, TATA sequence binding protein, TBP, TFIID, Transcription initiation factor TFIID TBP subunit, GTF2D1, MGC117320, MGC126054, MGC126055, SCA 17, SCA17, TATA binding factor, TATA box binding protein, TATA box factor, TATA sequence binding protein, TBP, TF2D, TFIID, Transcription initiation factor TFIID TBP subunit, CBP/p300, CREB binding protein, Cyclic AMP-responsive enhancer binding protein, RSTS, RTS, Rubinstein-Taybi syndrome.

    Background: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009].

    基因ID

    5956

    途径

    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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