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Cyclin E1 抗体 (pThr77) (Biotin)

This anti-Cyclin E1 antibody is a 兔 多克隆 antibody detecting Cyclin E1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN684495
发货至: 中国

Quick Overview for Cyclin E1 抗体 (pThr77) (Biotin) (ABIN684495)

抗原

See all Cyclin E1 (CCNE1) 抗体
Cyclin E1 (CCNE1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cyclin E1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA
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    pThr77

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Cyclin E around the phosphorylation site of Thr77

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Cyclin E1 (CCNE1)

    别名

    Cyclin E

    背景

    Synonyms: CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E, CCNE1_HUMAN.

    Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

    分子量

    47kDa

    基因ID

    898

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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