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EGFR 抗体 (pTyr998) (Biotin)

This anti-EGFR antibody is a 兔 多克隆 antibody detecting EGFR in WB 和 ELISA. Suitable for 人.
产品编号 ABIN684300
发货至: 中国

Quick Overview for EGFR 抗体 (pTyr998) (Biotin) (ABIN684300)

抗原

See all EGFR 抗体
EGFR (Epidermal Growth Factor Receptor (EGFR))

适用

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克隆类型

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多克隆

标记

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This EGFR antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA
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    pTyr998

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human EGFR around the phosphorylation site of Tyr998

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    别名

    EGFR

    背景

    Synonyms: Epidermal growth factor receptor, p170EGFR, ERBB1, HER1, Avian erythroblastic leukemia viral verbb oncogene homolog, EGF R, EGFR, erbb 1, Erbb, Erbb1, mENA, Oncogene ERBB, Receptor tyrosine protein kinase ErbB1, Urogastrone, wa2, Wa5

    Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.

    基因ID

    1956

    途径

    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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