CSF1R 抗体 (pTyr546) (Biotin)
Quick Overview for CSF1R 抗体 (pTyr546) (Biotin) (ABIN683745)
抗原
See all CSF1R 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr546
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 546
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:100-1000
IHC-P 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
-
别名
- M-Csf Receptor
-
背景
-
Synonyms: C FMS, CD 115, CD115, CD115 antigen, CFMS, Colony stimulating factor 1 receptor, Colony stimulating factor I receptor, CSF 1 R, CSF 1R, CSF1 R, CSF1R, CSFR, FIM 2, FIM2, CSF1R_HUMAN
Background: This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.
-
基因ID
- 1436
-
途径
- RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
抗原
-