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CSF1R 抗体 (pTyr546)

This anti-CSF1R antibody is a 兔 多克隆 antibody detecting CSF1R in WB, IHC (p) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN683743
发货至: 中国

Quick Overview for CSF1R 抗体 (pTyr546) (ABIN683743)

抗原

See all CSF1R 抗体
CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CSF1R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    pTyr546

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human CSF1R around the phosphorylation site of tyrosine 546

    亚型

    IgG
  • 应用备注

    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

    别名

    M-Csf Receptor

    背景

    Synonyms: C FMS, CD 115, CD115, CD115 antigen, CFMS, Colony stimulating factor 1 receptor, Colony stimulating factor I receptor, CSF 1 R, CSF 1R, CSF1 R, CSF1R, CSFR, FIM 2, FIM2, CSF1R_HUMAN

    Background: This protein tyrosine kinase transmembrane receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

    基因ID

    1436

    途径

    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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