HES1 抗体 (AA 41-150)
(3 references)Quick Overview for HES1 抗体 (AA 41-150) (ABIN682393)
抗原
See all HES1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-150
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HES1
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亚型
- IgG
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anti-Hes Family bHLH Transcription Factor 1 (HES1) (N-Term) antibody
HES1 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 斑马鱼, 马 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) antibodyHES1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 9-38) antibodyHES1 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 1-277) antibodyHES1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 24-35) antibodyHES1 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 马, 猴, Bat, 非洲爪蟾, Hamster WB, IHC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) antibodyHES1 适用: 人 ELISA, LMNX 宿主: 小鼠 Monoclonal OTI1B5 unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 21-251) antibodyHES1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) (N-Term) antibodyHES1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) antibodyHES1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 7B9 unconjugated
anti-Hes Family bHLH Transcription Factor 1 (HES1) antibodyMicroarray verified HES1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB869233 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately." in: Stem cell research & therapy, Vol. 6, pp. 120, (2015) (PubMed).
: "Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer." in: Scientific reports, Vol. 4, pp. 3963, (2014) (PubMed).
: "Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells." in: Neuroscience, Vol. 212, pp. 214-24, (2012) (PubMed).
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: "Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately." in: Stem cell research & therapy, Vol. 6, pp. 120, (2015) (PubMed).
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- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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别名
- HES1
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背景
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Synonyms: HHL, HRY, HES-1, bHLHb39, Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, HES1, HL
Background: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
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基因ID
- 3280
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UniProt
- Q14469
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途径
- DNA Damage Repair
抗原
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