FZD5 抗体 (PE-Cy5)
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北京 101111
Quick Overview for FZD5 抗体 (PE-Cy5) (ABIN681865)
抗原
See all FZD5 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Frizzled 5
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亚型
- IgG
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anti-Frizzled Family Receptor 5 (FZD5) (AA 72-161) antibody
FZD5 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 6A3 unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 151-217) antibodyFZD5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 461-510) antibodyFZD5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 467-516) antibodyFZD5 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (Cytoplasmic Domain) antibodyFZD5 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (N-Term) antibodyFZD5 适用: 人, 小鼠, 大鼠, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 72-161) antibodyFZD5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 1-585) antibodyFZD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 461-510) antibodyFZD5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (Middle Region) antibodyFZD5 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF (p) (1:100-500)
Not yet tested in other applications. Optimal working dilutions must be determined by the end user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Protect from light.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FZD5 (Frizzled Family Receptor 5 (FZD5))
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别名
- Frizzled 5
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背景
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Synonyms: C2orf31, Frizzled homolog 5, Frizzled-5, Frizzled5, Fz 5, Fz-5, Fz5, FZD 5, hFz5, FZD5, FZD5_HUMAN, FzE 5, FzE5, HFZ 5, Seven transmembrane receptor frizzled 5, Wnt receptor, hFz8, Fz-8, Frizzled-8, FZD8.
Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 5 protein is believed to be the receptor for the Wnt5A ligand. Frizzled 5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. Frizzled 5 was cloned from a retina cDNA library. Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1.
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分子量
- 62 kDa
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基因ID
- 7855, 8325
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途径
- WNT signaling
抗原
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