LRP6 抗体 (PE)
Quick Overview for LRP6 抗体 (PE) (ABIN681488)
抗原
See all LRP6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Excitation / Emission Wavelengths: 565nm/578nm
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交叉反应
- 大鼠, 犬, 猪, 牛
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纯化方法
- purified by Protein A
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免疫原
- KLH conjugated synthetic peptide derived from human LRP6
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亚型
- IgG
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说明
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Excitation / Emission wavelength: 496nm / 578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 µg/µL
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4 °C for 12 months
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有效期
- 12 months
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- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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别名
- LRP6
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背景
- This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
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分子量
- 177kDa
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基因ID
- 4040
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途径
- WNT signaling, Tube Formation
抗原
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