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CDC25A 抗体 (AA 451-524)

Cited in 1 publication. This 兔 多克隆 anti-CDC25A antibody specifically detects CDC25A in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN680263
发货至: 中国
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Quick Overview for CDC25A 抗体 (AA 451-524) (ABIN680263)

抗原

See all CDC25A 抗体
CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

适用

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人, 小鼠, 大鼠

宿主

  • 213
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克隆类型

  • 214
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多克隆

标记

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This CDC25A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 451-524

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    synthetic peptide from human cdc25A conjugated to KLH

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Wei, Zhang, Ren, Zhang, Liu, Duan, Yu, Li, Peng, Zhou, Sun: "Endosulfan induces cell dysfunction through cycle arrest resulting from DNA damage and DNA damage response signaling pathways." in: The Science of the total environment, Vol. 589, pp. 97-106, (2017) (PubMed).

  • 抗原

    CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

    别名

    Cdc25A

    背景

    Synonyms: Cdc 25a, CDC25A2, Cell division cycle 25 homolog A S. pombe, Cell division cycle 25A, Cell division cycle 25A isoform a, Cell division cycle 25A isoform bv, D9Ertd393ev, Dual specicity phosphatase CDC25A, EC 3.1.3.48, M phase inducer phosphatase 1, MGC115549.

    Background: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

    基因ID

    993

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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