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NOTCH2 抗体 (AA 1501-1700)

This anti-NOTCH2 antibody is a 兔 多克隆 antibody detecting NOTCH2 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN680183
发货至: 中国

Quick Overview for NOTCH2 抗体 (AA 1501-1700) (ABIN680183)

抗原

See all NOTCH2 抗体
NOTCH2 (Notch 2 (NOTCH2))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This NOTCH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 1501-1700

    交叉反应

    人, 小鼠

    预测反应

    Rat,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Notch2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    NOTCH2 (Notch 2 (NOTCH2))

    别名

    Notch 2

    背景

    Synonyms: hN2, AGS2, HJCYS, Neurogenic locus notch homolog protein 2, Notch 2, NOTCH2

    Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation.

    基因ID

    4853

    UniProt

    Q04721

    途径

    Notch Signaling, Stem Cell Maintenance
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