DKK1 抗体 (AA 201-266)
(3 references)Quick Overview for DKK1 抗体 (AA 201-266) (ABIN678158)
抗原
See all DKK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-266
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交叉反应
- 犬, 人
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预测反应
- Mouse,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DKK1
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亚型
- IgG
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anti-Dickkopf Homolog 1 (DKK1) (AA 1-266) antibody
DKK1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB52126 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 1-266) antibodyDKK1 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibodyDKK1 适用: 人 WB 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 81-180) antibodyDKK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C10 unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 36-260) antibodyDKK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibodyDKK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibodyDKK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (Internal Region) antibodyDKK1 适用: 人, 马, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (C-Term) antibodyVerified DKK1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Dickkopf Homolog 1 (DKK1) (Internal Region) antibodyDKK1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "TET1 inhibits EMT of ovarian cancer cells through activating Wnt/β-catenin signaling inhibitors DKK1 and SFRP2." in: Gynecologic oncology, Vol. 147, Issue 2, pp. 408-417, (2017) (PubMed).
: "Expression of Wnt3a, Wnt10b, ?-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." in: Acta odontologica Scandinavica, pp. 1-7, (2015) (PubMed).
: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, (2014) (PubMed).
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: "TET1 inhibits EMT of ovarian cancer cells through activating Wnt/β-catenin signaling inhibitors DKK1 and SFRP2." in: Gynecologic oncology, Vol. 147, Issue 2, pp. 408-417, (2017) (PubMed).
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- DKK1 (Dickkopf Homolog 1 (DKK1))
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别名
- DKK1
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背景
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Synonyms: SK, DKK-1, Dickkopf-related protein 1, Dickkopf-1, hDkk-1, DKK1, UNQ492/PRO18
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
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基因ID
- 22943
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UniProt
- O94907
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途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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