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PYCARD 抗体 (AA 121-170)

Cited in 4+ publications. This anti-PYCARD antibody is a 兔 多克隆 antibody detecting PYCARD in WB. Suitable for 人 和 大鼠.
产品编号 ABIN6746135
发货至: 中国
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Quick Overview for PYCARD 抗体 (AA 121-170) (ABIN6746135)

抗原

See all PYCARD 抗体
PYCARD (PYD and CARD Domain Containing (PYCARD))

适用

  • 64
  • 11
  • 10
  • 1
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  • 1
人, 大鼠

宿主

  • 55
  • 9
  • 3

克隆类型

  • 44
  • 23
多克隆

标记

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  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
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  • 1
  • 1
This PYCARD antibody is un-conjugated

应用范围

  • 48
  • 24
  • 24
  • 17
  • 17
  • 16
  • 6
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 6
    • 6
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 121-170

    特异性

    Human PYCARD

    预测反应

    Percent identity by BLAST analysis:

    纯化方法

    Immunoaffinity purified

    免疫原

    Synthetic peptide located between aa121-170 of human PYCARD (Q9ULZ3, NP_037390). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%), Marmoset (92%), Hamster, Panda, Bat, Rabbit, Horse, Pig (85%), Rat (78%).

    Type of Immunogen: Synthetic peptide
  • 应用备注

    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS with 2 % sucrose

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Nakashio, Fujita, Rokudai, Sato, Tsuruo: "Prevention of phosphatidylinositol 3'-kinase-Akt survival signaling pathway during topotecan-induced apoptosis." in: Cancer research, Vol. 60, Issue 18, pp. 5303-9, (2000) (PubMed).

    Auphan, DiDonato, Rosette, Helmberg, Karin: "Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis." in: Science (New York, N.Y.), Vol. 270, Issue 5234, pp. 286-90, (1995) (PubMed).

    Cordle, Donald, Read, Hawiger: "Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells." in: The Journal of biological chemistry, Vol. 268, Issue 16, pp. 11803-10, (1993) (PubMed).

    Haskill, Beg, Tompkins, Morris, Yurochko, Sampson-Johannes, Mondal, Ralph, Baldwin: "Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity." in: Cell, Vol. 65, Issue 7, pp. 1281-9, (1991) (PubMed).

  • 抗原

    PYCARD (PYD and CARD Domain Containing (PYCARD))

    别名

    PYCARD / ASC

    背景

    Name/Gene ID: PYCARD
    Family: Apoptosis

    Synonyms: PYCARD, CARD5, HASC, ASC, TMS, TMS-1, PYD and CARD domain containing, TMS1

    基因ID

    29108

    NCBI登录号

    NP_037390

    UniProt

    Q9ULZ3

    途径

    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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