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GRP78 抗体 (AA 251-360)

HSPA5 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN673554
发货至: 中国
  • 抗原 See all GRP78 (HSPA5) 抗体
    GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
    抗原表位
    • 23
    • 15
    • 13
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
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    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    AA 251-360
    适用
    • 195
    • 123
    • 106
    • 36
    • 35
    • 34
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    • 30
    • 20
    • 14
    • 5
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    • 3
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 135
    • 97
    • 8
    • 3
    • 1
    • 1
    克隆类型
    • 139
    • 107
    多克隆
    标记
    • 99
    • 19
    • 16
    • 12
    • 12
    • 12
    • 9
    • 8
    • 8
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    • 3
    • 3
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GRP78 antibody is un-conjugated
    应用范围
    • 213
    • 98
    • 87
    • 79
    • 78
    • 34
    • 28
    • 26
    • 25
    • 20
    • 12
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GRP78
    亚型
    IgG
    Top Product
    Discover our top product HSPA5 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Xia, Ji, Xu, Lin, Wang, Xia, Lv, Song, Ma, Chen: "Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress." in: Cell death & disease, Vol. 8, Issue 7, pp. e2957, (2018) (PubMed).

    Chen, Wang, Chen, Wang, Gui, Dai, Fang, Zhang, Lu: "Influence of resveratrol on endoplasmic reticulum stress and expression of adipokines in adipose tissues/adipocytes induced by high-calorie diet or palmitic acid." in: Endocrine, Vol. 55, Issue 3, pp. 773-785, (2017) (PubMed).

    Tian, Liu, Qu: "Role of endoplasmic reticulum stress on cisplatin resistance in ovarian carcinoma." in: Oncology letters, Vol. 13, Issue 3, pp. 1437-1443, (2017) (PubMed).

    Wei, Gao, Wang, Zhao, Sun: "Excessive fluoride induces endoplasmic reticulum stress and interferes enamel proteinases secretion." in: Environmental toxicology, Vol. 28, Issue 6, pp. 332-41, (2013) (PubMed).

    Du, Zhou, Jia, Huang: "SelK is a novel ER stress-regulated protein and protects HepG2 cells from ER stress agent-induced apoptosis." in: Archives of biochemistry and biophysics, Vol. 502, Issue 2, pp. 137-43, (2010) (PubMed).

  • 抗原
    GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
    别名
    GRP78 (HSPA5 产品)
    背景

    Synonyms: BIP, MIF2, GRP78, HEL-S-89n, 78 kDa glucose-regulated protein, GRP-78, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 7 kDa protein 5, Immunoglobulin heavy chain-binding protein, HSPA5

    Background: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC1, probably to facilitate the release of DNAJC1 from its substrate.

    基因ID
    3309
    UniProt
    P11021
    途径
    Thyroid Hormone Synthesis, ER-Nucleus Signaling
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