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PD-L1 抗体

This anti-PD-L1 antibody is a 小鼠 单克隆 antibody detecting PD-L1 in FACS. Suitable for 人.
产品编号 ABIN6727426
发货至: 中国

Quick Overview for PD-L1 抗体 (ABIN6727426)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

适用

  • 274
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宿主

  • 154
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小鼠

克隆类型

  • 204
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  • 7
单克隆

标记

  • 158
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This PD-L1 antibody is un-conjugated

应用范围

  • 194
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Flow Cytometry (FACS)

克隆位点

29E-2A3
  • 纯化方法

    Purified

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Matching Isotype Control: Purified Mouse IgG2b, κ Isotype Control (ABIN7469802)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    PD-L1

    背景

    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.

    基因ID

    29126

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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