BIRC7 抗体 (AA 101-200) (Cy3)
Quick Overview for BIRC7 抗体 (AA 101-200) (Cy3) (ABIN672564)
抗原
See all BIRC7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Livin
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亚型
- IgG
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anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 101-200) antibody
BIRC7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibodyBIRC7 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyVerified BIRC7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibodyBIRC7 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-90) antibodyBIRC7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 87-298) antibodyBIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyBIRC7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-265) antibodyBIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibodyBIRC7 适用: 人, Cow, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-298) antibodyBIRC7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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别名
- Livin
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背景
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Synonyms: KIAP, LIVIN, MLIAP, RNF50, ML-IAP, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, RING finger protein 50, BIRC7, UNQ5800/PRO19607/PRO21344
Background: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
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基因ID
- 79444
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UniProt
- Q96CA5
抗原
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