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NOTCH3 抗体 (PE)

The PE-conjugated 小鼠 单克隆 anti-NOTCH3 antibody (Clone MHN3-21) (ABIN6722241) specifically detects NOTCH3 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6722241
发货至: 中国
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Quick Overview for NOTCH3 抗体 (PE) (ABIN6722241)

抗原

See all NOTCH3 抗体
NOTCH3 (Notch 3 (NOTCH3))

适用

  • 57
  • 19
  • 11
  • 1

宿主

  • 42
  • 15
  • 3
  • 1
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 46
  • 19
单克隆

标记

  • 35
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This NOTCH3 antibody is conjugated to PE

应用范围

  • 27
  • 25
  • 22
  • 7
  • 7
  • 4
  • 4
  • 3
  • 2
  • 1
Flow Cytometry (FACS)

克隆位点

MHN3-21
  • 亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    Notch3

    背景

    Synonyms: NOTCH3,Notch 3,Notch 3 extracellular truncation,Notch 3 intracellular domain

    Background: The Notch receptors are highly conserved from invertebrates to mammals. While Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences. The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. Notch 3 is primarily expressed in adult arterial smooth muscle cells. Notch3 gene mutation can cause CADASIL, a hereditary early stroke syndrome.

    基因ID

    4854

    UniProt

    Q9UM47

    途径

    Notch Signaling
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