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JAK3 抗体 (AA 406-661)

This anti-JAK3 antibody is a 兔多克隆 antibody detecting JAK3 in WB 和 ELISA. Suitable for 人.

产品编号 ABIN6719493

发货至: 中国

Quick Overview for JAK3 抗体 (AA 406-661) (ABIN6719493)

抗原

See all JAK3 抗体

JAK3 (Janus Kinase 3 (JAK3))

适用

80
45
21
2
2
2
2
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

43
7
4
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1

This JAK3 antibody is un-conjugated

应用范围

54
30
18
17
14
14
12
12
8
8
3
1
1

Western Blotting (WB), ELISA

Discover our top product JAK3 Primary Antibody

抗原表位
16

8

7

5

4

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 406-661

原理

Anti-JAK3 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-JAK3 Antibody Picoband® (ABIN6719493). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human JAK3 recombinant protein (Position: Q406-D661).

亚型

IgG
anti-Janus Kinase 3 (JAK3) (AA 716-967) antibody
JAK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) antibody
JAK3 适用: 人, 小鼠 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H2 unconjugated

anti-Janus Kinase 3 (JAK3) (AA 601-700) antibody
JAK3 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) antibody
JAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (pTyr980), (pTyr981) antibody
JAK3 适用: 人 ELISA 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (Tyr785) antibody
JAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (AA 750-850) antibody
JAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) (AA 751-800) antibody
JAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Janus Kinase 3 (JAK3) antibody
JAK3 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 1C7 unconjugated Recombinant Antibody

anti-Janus Kinase 3 (JAK3) (pTyr785) antibody
JAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Riedy MC, Dutra AS, Blake TB, Modi W, Lal BK, Davis J, Bosse A, O'Shea JJ, Johnston JA (October 1996). "Genomic sequence, organization, and chromosomal localization of human JAK3". Genomics. 37 (1): 57-61. 2. Hoffman SM, Lai KS, Tomfohrde J, Bowcock A, Gordon LA, Mohrenweiser HW (July 1997). "JAK3 maps to human chromosome 19p12 within a cluster of proto-oncogenes and transcription factors". Genomics. 43 (1): 109-11.

说明

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

JAK3 (Janus Kinase 3 (JAK3))

别名

JAK3

背景

Synonyms: Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3, Leukocyte janus kinase, L-JAK, JAK3
Tissue Specificity: In NK cells and an NK-like cell line but not in resting T-cells or in other tissues. The S-form is more commonly seen in hematopoietic lines, whereas the B-form is detected in cells both of hematopoietic and epithelial origins.
Background: Tyrosine-protein kinase JAK3 is an enzyme that in humans is encoded by the JAK3 gene. It is mapped to 19p13.11. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

分子量

125 kDa

基因ID

3718

UniProt

P52333

途径

JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response

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