JAK3 抗体 (AA 406-661)
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北京 101111
Quick Overview for JAK3 抗体 (AA 406-661) (ABIN6719493)
抗原
See all JAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 406-661
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原理
- Anti-JAK3 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-JAK3 Antibody (ABIN6719493). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human JAK3 recombinant protein (Position: Q406-D661).
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亚型
- IgG
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anti-Janus Kinase 3 (JAK3) (AA 716-967) antibody
JAK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) antibodyJAK3 适用: 人, 小鼠 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H2 unconjugated
anti-Janus Kinase 3 (JAK3) (AA 601-700) antibodyJAK3 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) antibodyJAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (pTyr980), (pTyr981) antibodyJAK3 适用: 人 ELISA 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (AA 750-850) antibodyJAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (Tyr785) antibodyJAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (AA 751-800) antibodyJAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) antibodyJAK3 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 1C7 unconjugated Recombinant Antibody
anti-Janus Kinase 3 (JAK3) (pTyr785) antibodyJAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
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说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- JAK3 (Janus Kinase 3 (JAK3))
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别名
- JAK3
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背景
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Synonyms: Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3, Leukocyte janus kinase, L-JAK, JAK3
Tissue Specificity: In NK cells and an NK-like cell line but not in resting T-cells or in other tissues. The S-form is more commonly seen in hematopoietic lines, whereas the B-form is detected in cells both of hematopoietic and epithelial origins.
Background: Tyrosine-protein kinase JAK3 is an enzyme that in humans is encoded by the JAK3 gene. It is mapped to 19p13.11. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
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分子量
- 125 kDa
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基因ID
- 3718
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UniProt
- P52333
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
抗原
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