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BID 抗体 (AA 1-195) (DyLight 550)

This anti-BID antibody is a 兔 多克隆 antibody detecting BID in FACS. Suitable for 人.
产品编号 ABIN7354548
发货至: 中国

Quick Overview for BID 抗体 (AA 1-195) (DyLight 550) (ABIN7354548)

抗原

See all BID 抗体
BID (BH3 Interacting Domain Death Agonist (BID))

适用

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宿主

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克隆类型

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多克隆

标记

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This BID antibody is conjugated to DyLight 550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-195

    原理

    Anti-Human Bid DyLight® 550 conjugated Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Human Bid DyLight® 550 conjugated Antibody (ABIN5518895)-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Bid recombinant protein (Position: M1-D195). Human Bid shares 64% and 61% amino acid (aa) sequence identity with mouse and rat Bid, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Chou, J. J., Li, H., Salvesen, G. S., Yuan, J., Wagner, G. Solution structure of BID, an intracellular amplifier of apoptotic signaling. Cell 95: 615-624, 1999. 2. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., Wang, X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94: 481-490, 1998. 3. Wang, K., Yin, X.-M., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Keck, C. L., Zimonjic, D. B., Popescu, N. C., Korsmeyer, S. J. BID, a proapoptotic BCL-2 family member, is localized to mouse chromosome 6 and human chromosome 22q11. Genomics 53: 235-238, 1998.

    说明

    Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
  • 抗原

    BID (BH3 Interacting Domain Death Agonist (BID))

    别名

    BID

    背景

    Synonyms: BH3-interacting domain death agonist, p22 BID, BID, BH3-interacting domain death agonist p15, p15 BID, BH3-interacting domain death agonist p13, p13 BID, BH3-interacting domain death agonist p11, p11 BID, BID

    Tissue Specificity: Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).

    Background: BID (BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2 family of proteins consists of both antagonists and agonists that regulate apoptosis and compete through dimerization. By fluorescence in situ hybridization, Wang et al. (1998) mapped the human BID gene to 22q11. Luo et al. (1998) reported the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as FAS and TNF.

    分子量

    39 kDa

    基因ID

    637

    UniProt

    P55957

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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