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AKT2 抗体 (C-Term)

The 小鼠 单克隆 anti-AKT2 antibody is suitable to detect AKT2 in samples from 人. It has been validated for WB, IF, FACS 和 ICC.
产品编号 ABIN6719267
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for AKT2 抗体 (C-Term) (ABIN6719267)

抗原

See all AKT2 抗体
AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This AKT2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

10C6
  • 抗原表位

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    C-Term

    原理

    Anti-AKT2 Antibody (monoclonal, 10C6)

    序列

    DRYDSLGLLE LDQRTHFPQF SYSASIRE

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    different from the related mouse sequence by two amino acids,and from the related rat sequence by one amino acid.

    产品特性

    Anti-AKT2 Antibody.(monoclonal, 10C6)-1. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.

    纯化方法

    Affinity-chromatography

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human AKT2, different from the related mouse sequence by two amino acids, and from the related rat sequence by one amino acid.

    亚型

    IgG1
  • 应用备注

    Western blot, 0.1-0.5 μg/mL Immunocytochemistry/Immunofluorescence, 2 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x106 cells

    说明

    Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

    别名

    AKT2

    背景

    Background: AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. This gene is mapped to 19q13.2. AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT2 seems also to be the principal isoform responsible of the regulation of glucose uptake. AKT2 is also specifically involved in skeletal muscle differentiation, one of its substrates in this process being ANKRD2. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers.

    Gene Full Name: AKT serine/threonine kinase 2

    分子量

    56 kDa

    基因ID

    208

    UniProt

    P31751

    途径

    PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
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