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CD44 抗体 (AA 701-742)

This anti-CD44 antibody is a 兔 多克隆 antibody detecting CD44 in FACS, WB, ELISA, IHC (p), IF (cc) 和 IF (p). Suitable for 人, 小鼠, 大鼠 和 兔. This Primary Antibody has been cited in 9+ publications.
产品编号 ABIN669591
发货至: 中国

Quick Overview for CD44 抗体 (AA 701-742) (ABIN669591)

抗原

See all CD44 抗体
CD44

适用

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人, 小鼠, 大鼠, 兔

宿主

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克隆类型

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多克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 701-742

    交叉反应

    人, 小鼠, 兔, 大鼠

    预测反应

    Dog,Cow,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CD44

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Neal, Boyle, Budge, Safadi, Richardson: "The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 73, (2019) (PubMed).

    Zhu, Meng, Wang, Wang, Zhang, Li, Li, Tan, Yang, Huang: "Effects of neuritin on the differentiation of bone marrow‑derived mesenchymal stem cells into neuron‑like cells." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 3201-3207, (2018) (PubMed).

    Liao, Zhong, Liu, Li, Ling, Zou: "Bone mesenchymal stem cells co-expressing VEGF and BMP-6 genes to combat avascular necrosis of the femoral head." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 954-962, (2018) (PubMed).

    Xu, Qin, Tan, Liu, Huang: "NIBP impacts on the expression of E-cadherin, CD44 and vimentin in colon cancer via the NF-κB pathway." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 5379-85, (2017) (PubMed).

    Wu, Zhu, Sun, Hu: "Subchondral bone changes and chondrogenic capacity of progenitor cells from subchondral bone in the collagenase-induced temporomandibular joints osteoarthritis rabbit model." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 9782-9, (2016) (PubMed).

    Wang, Zou, Deng, Fu, Li, Wu, Wang, Liu: "Characterization of sphere?forming cells with stem?like properties from the gastric cancer cell lines MKN45 and SGC7901." in: Molecular medicine reports, Vol. 10, Issue 6, pp. 2937-41, (2014) (PubMed).

  • 抗原

    CD44

    别名

    CD44

    背景

    Synonyms: IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III, CD44 antigen, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44

    Background: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

    基因ID

    960

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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