FADD 抗体 (AA 1-80) (Cy3)
Our Local Distributor
北京 101111
Quick Overview for FADD 抗体 (AA 1-80) (Cy3) (ABIN669474)
抗原
See all FADD 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-80
-
原理
- FADD Polyclonal Antibody, Cy3 Conjugated
-
交叉反应
- 人, 大鼠
-
预测反应
- Mouse,Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from mouse FADD
-
亚型
- IgG
-
-
-
-
应用备注
- WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
-
别名
- FADD
-
背景
-
Synonyms: Mort1/FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Protein FADD, Fadd, Mort1
Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).
-
基因ID
- 14082
-
UniProt
- Q61160
-
途径
- Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
抗原
-