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Angiotensin I Converting Enzyme 1 抗体 (AA 801-900)

This anti-Angiotensin I Converting Enzyme 1 antibody is a 兔 多克隆 antibody detecting Angiotensin I Converting Enzyme 1 in WB, ELISA, FACS, ICC, IF (p), IF (cc), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 犬. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN668631
发货至: 中国

Quick Overview for Angiotensin I Converting Enzyme 1 抗体 (AA 801-900) (ABIN668631)

抗原

See all Angiotensin I Converting Enzyme 1 (ACE) 抗体
Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

适用

  • 122
  • 61
  • 50
  • 20
  • 15
  • 9
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 犬

宿主

  • 108
  • 43
  • 3
  • 1
  • 1
  • 1

克隆类型

  • 101
  • 56
多克隆

标记

  • 78
  • 18
  • 9
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Angiotensin I Converting Enzyme 1 antibody is un-conjugated

应用范围

  • 114
  • 66
  • 41
  • 40
  • 32
  • 25
  • 25
  • 24
  • 10
  • 10
  • 9
  • 6
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 16
    • 15
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 801-900

    交叉反应

    犬, 人, 小鼠, 大鼠

    预测反应

    Cow,Sheep,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from Human ACE1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Jiang, Li, Lu, Wang, Yu, Sui, Fu: "Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats." in: Experimental and therapeutic medicine, Vol. 14, Issue 5, pp. 4977-4985, (2017) (PubMed).

    Liu, Jiang, Zhang, Li, Li, Xie, Hu: "Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).

  • 抗原

    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

    别名

    ACE

    背景

    Synonyms: Angiotensin Converting Enzyme 1, ACE, ACE-T, Dipeptidyl carboxy peptidase 1, Kininase II, ACE-1, testis-specic isoform precursor, ACE1, Angiotensin converting enzyme testis specic isoform, Carboxycathepsin, CD 143, DCP 1, Dipeptidyl carboxypeptidase 1, MVCD3, Peptidase P, Peptidyl dipeptidase A, Testicular ECA

    Background: Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

    基因ID

    1636

    UniProt

    P12821

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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