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- 抗原 See all PAK1/2/3 抗体
- PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))
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抗原表位
- pThr402
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK1/2/3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- Supplier Product No.
- 612-401-e05
- Supplier
- Rockland
- 原理
- PAK 1/2/3 phospho T402 Antibody
- 交叉反应 （详细）
- Anti-PAK 1/2/3 pT402 antibody is directed against rat PAK protein.
- 纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification and is specific for the phosphorylated protein.
- 免疫原
- Anti-PAK 1/2/3 pT402 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Thr402.
- 亚型
- IgG
- Top Product
- Discover our top product PAK1/2/3 Primary Antibody
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anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (Thr402), (Thr421), (Thr423) antibody
PAK1/2/3 适用: 人 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (Thr402), (Thr421), (Thr423) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (pThr423) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (AA 391-440) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinases 1/2/3 (PAK1/2/3) (AA 111-160), (pSer144) antibodyPAK1/2/3 适用: 人, 大鼠, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western_Blot_Dilution: 1:1000
Other: User Optimized
- 说明
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Anti-PAK 1/2/3 pT402 Antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 68-70 kDa in size corresponding to PAK proteins phosphorylated at Thr402 in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))
- 别名
- PAK 1/2/3 (PAK1/2/3 产品)
- 背景
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Synonyms: Serine/threonine-protein kinase PAK 1, Alpha-PAK, Protein kinase MUK2, p21-activated kinase 1, p68-PAK
Background: PAK 1/2/3 pT402 Antibody detects PAK 1/2/3 pT402 proteins. In mammals, there are several identified isoforms of p21-activated protein kinases or PAKs: α-PAK (also known as PAK-1) and β-PAK (also known as PAK-3) are mostly brain-specific, while -PAK (also known as PAK-2) is expressed ubiquitously. Mutations of the gene coding for PAK-3 are associated with X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus. PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death. Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK. Anti-PAK 1/2/3 pT402 Antibody is ideal for investigators involved in Neuroscience and Apoptosis research.
Gene Name: PAK1-3
- 基因ID
- 29431
- UniProt
- P35465
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