MAP2K5 抗体 (pSer311, pThr315)
Quick Overview for MAP2K5 抗体 (pSer311, pThr315) (ABIN6658265)
抗原
See all MAP2K5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer311, pThr315
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Supplier Product No.
- 612-401-d74
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Supplier
- Rockland
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原理
- MEK5 phospho S311/phospho T315 Antibody
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交叉反应 （详细）
- MEK5 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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纯化方法
- Anti-MEK5 pS311/pT315 antibody is directed against rat MEK5.
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免疫原
- Anti-MEK5 pS311/pT315 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser311/Thr315 conjugated to KLH.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 251-350) antibody
MAP2K5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-448) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal M1-E6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-120) antibodyMAP2K5 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1E5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 1-190) antibodyMAP2K5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 385-412), (C-Term) antibodyMAP2K5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (pSer137) antibodyMAP2K5 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5) (AA 311-315) antibodyMAP2K5 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-MEK5 pS311/pT315 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 49 kDa in size corresponding to MEK5 protein phosphorylated at Ser311/Thr315 in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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别名
- MEK5
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背景
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Synonyms: Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5
Background: MEK5 pS311/pT315 antibody detects MEK5 that is phosphorylated at Ser311 and Threonine315. MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 whereas MEK5 itself is regulated by MEKK3. An important link between MEK5 and metastatic prostrate cancer has been demonstrated. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation. Therefore, MEK5 pS311/pT315 antibody is ideal for investigators involved in Cell Signaling, Cell Migration and Proliferation and, more generally in Cancer Research.
Gene Name: MAP2K5
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基因ID
- 29568
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UniProt
- Q62862
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway
抗原
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