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SYN1 抗体 (pSer9)

This anti-SYN1 antibody is a 兔 多克隆 antibody detecting SYN1 in WB 和 IHC. Suitable for 大鼠.
Rockland
产品编号 ABIN6658201
Supplier Product No.: 612-401-c93
发货至: 中国

Quick Overview for SYN1 抗体 (pSer9) (ABIN6658201)

抗原

See all SYN1 抗体
SYN1 (Synapsin I (SYN1))

适用

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  • 92
  • 70
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大鼠

宿主

  • 126
  • 8

克隆类型

  • 117
  • 17
多克隆

标记

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This SYN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pSer9

    Supplier Product No.

    612-401-c93

    Supplier

    Rockland

    原理

    Synapsin I phospho S9 Antibody

    交叉反应 (详细)

    The antibody detects the phosphorylated S9 amino acid.

    纯化方法

    Anti-Synapsin I pS9 antibody is directed against rat Synapsin I.

    免疫原

    Anti-Synapsin I pS9 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser9 of Synapsin I.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry_Dilution: 1:500

    Western_Blot_Dilution: 1:1000

    说明

    Anti-Synapsin I pS9 (Rabbit) antibody is tested for use in Western Blotting and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet protein phosphorylated at Ser9 in the appropriate cell lysate or extract. This antibody also weakly labels the approximately 55 kDa synapsin II protein which has a similar phosphorylation site to that of Ser9 on synapsin I. Researchers should determine optimal titers for applications that are not stated below.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    SYN1 (Synapsin I (SYN1))

    别名

    Synapsin I

    背景

    Synonyms: Synapsin I, SYN1

    Background: Synapsin I pS9 antibody is directed against rat Synapsin I, which plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the expression of synapsin I is a precise indicator of synapse formation. Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I. Phosphorylation of this site is thought to regulate synaptic vesicle function and neurite outgrowth. Anti-Synapsin I pS9 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

    Gene Name: SYN1

    基因ID

    24949

    NCBI登录号

    NP_001104252

    UniProt

    P09951
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