SYN1 抗体 (pSer603)
(2 references)
Quick Overview for SYN1 抗体 (pSer603) (ABIN6658200)
抗原
See all SYN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer603
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Supplier Product No.
- 612-401-c95
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Supplier
- Rockland
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原理
- Synapsin I phospho S603 Antibody
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交叉反应 （详细）
- The antibody detects Synapsin I that is phosphorylated at S603.
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纯化方法
- Anti-Synapsin I pS603 antibody is directed against bovine Synapsin I.
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免疫原
- Anti-Synapsin I pS603 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 of Synapsin I.
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亚型
- IgG
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anti-Synapsin I (SYN1) (AA 362-511) antibody
SYN1 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7H10G6 unconjugated
anti-Synapsin I (SYN1) (AA 113-420) antibodySYN1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (AA 362-450) antibodySYN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) antibodySYN1 适用: 人, 大鼠, 小鼠, Cow WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer62), (pSer67) antibodySYN1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer549) antibodySYN1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synapsin I (SYN1) (AA 201-300) antibodySYN1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Anti-Synapsin I pS603 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 78 kDa in size corresponding to synapsin I doublet protein phosphorylated at Ser603.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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: "The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation." in: PLoS biology, Vol. 17, Issue 3, pp. e3000170, (2019) (PubMed).
: "Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation." in: Frontiers in cellular neuroscience, Vol. 9, pp. 505, (2016) (PubMed).
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: "The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation." in: PLoS biology, Vol. 17, Issue 3, pp. e3000170, (2019) (PubMed).
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- SYN1 (Synapsin I (SYN1))
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别名
- Synapsin I
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背景
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Synonyms: Synapsin I, SYN1
Background: Synapsin I pS603 antibody is directed against rat Synapsin I, whcih plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 603 is the site on synapsin I that is phosphorylated by calcium calmodulin kinase II and by p21-activated kinases. Phosphorylation of this site is thought to regulate synaptic vesicle function. Anti-Synapsin I pS603 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: SYN1
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基因ID
- 24949
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NCBI登录号
- NP_001104252
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UniProt
- P09951
抗原
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