CD40 抗体 (N-Term)
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北京 101111
Quick Overview for CD40 抗体 (N-Term) (ABIN6657891)
抗原
See all CD40 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-p53
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Supplier
- Rockland
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原理
- CD40 Antibody
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交叉反应 (详细)
- Anti-CD40 antibody is directed against mouse CD40 protein.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- CD40 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the N-terminal of mouse CD40.
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亚型
- IgG
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应用备注
- Optional[Neutralization_Dilution]: 0.5 μg/mL
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说明
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Anti-CD40 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~32.1 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 200μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. After reconstitution, at 4°C for one month. Aliquot and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CD40
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别名
- CD40
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背景
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Synonyms: B-cell surface antigen CD40,Bp50,CD40L receptor,CD_antigen=CD40,
Background: CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium .CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin. This antibody is suitable for researchers interested in cancer research.
Gene Name: CD40
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基因ID
- 21939
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NCBI登录号
- NP_035741
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UniProt
- P27512
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途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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