TFAM 抗体 (C-Term)
Quick Overview for TFAM 抗体 (C-Term) (ABIN6657693)
抗原
See all TFAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 100-401-x30
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Supplier
- Rockland
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原理
- TFAM Antibody
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纯化方法
- Anti-TFAM Antibody is a prepared sterile filtered neat serum.
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过滤
- Sterile filtered
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免疫原
- Anti-TFAM Antibody was produced in rabbits by repeated immunizations with a native recombinant mouse TFAM protein with c-terminal 6-his tag.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:20,000
Western_Blot_Dilution: 1:2000
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说明
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Anti-TFAM Antibody has been tested in Western Blots and is specific for the ~24 kDa TFAM protein. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
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有效期
- 12 months
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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别名
- TFAM
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背景
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Synonyms: Transciption factor A mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG
Background: Mitochondrial Transcription Factor A (TFAM) is a key activator of mitochondrial (mt) DNA transcription as well as a participant in mitochondrial genome replication. mtDNA is highly susceptible to oxidative stress leading to mitochondrial dysfunction. Overexpression of TFAM has been implicated in the amelioration of age dependent impairment of brain functions through the prevention of oxidative stress and mitochondrial dysfunction in microglia. More recently, TFAM overexpression has been shown to potentially reduce oxidative stress in motor neurons and delay onset of amyotrophic lateral sclerosis (ALS) in ALS model mice. TFAM Antibody is ideal for researchers interested in neuroscience research.
Gene Name: TFAM
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基因ID
- 21780
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NCBI登录号
- NP_033386
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UniProt
- P40630
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途径
- Chromatin Binding
抗原
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