Periostin 抗体 (C-Term)
Quick Overview for Periostin 抗体 (C-Term) (ABIN6657608)
抗原
See all Periostin (POSTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 600-401-e09
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Supplier
- Rockland
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原理
- Periostin Antibody
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交叉反应 (详细)
- Anti-Periostin antibody is directed against mouse Periostin protein.
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纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-Periostin Antibody was produced by repeated immunizations with bacterial fusion proteins equivalent to a 188 amino acid polypeptide from the C-terminal region of mouse periostin which is comprised of six small alternatively spliced exons.
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亚型
- IgG
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应用备注
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Immunohistochemistry_Dilution: 1:100
Western_Blot_Dilution: 1:1000
Other: User Optimized
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说明
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Anti-Periostin Antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 93 kDa in size corresponding to periostin doublet in mouse lung extract. The antibody works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90° C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- Periostin (POSTN)
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别名
- Periostin
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背景
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Synonyms: PN, Osteoblast-specific factor 2, OSF-2
Background: Periostin Antibody detects Periostin protein. Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Periostin has since been demonstrated to be important in heart valve development and myocardial infarction because it promotes collagen fibrogenesis, inhibits differentiation of progenitor cells into cardiomyocytes and is essential in maintaining the biomechanical properties of the adult myocardium. Anti-Periostin Antibody is ideal for investigators involved in Cancer and Cardiovascular research.
Gene Name: POSTN
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基因ID
- 50706
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UniProt
- Q62009
抗原
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