GDNF 抗体 (Internal Region)
Quick Overview for GDNF 抗体 (Internal Region) (ABIN6657513)
抗原
See all GDNF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 600-401-r08
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Supplier
- Rockland
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原理
- GDNF Antibody
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交叉反应 （详细）
- Anti-GDNF antibody is directed against human GDNF protein.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- GDNF affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human GDNF.
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亚型
- IgG
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anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 121-211) antibody
GDNF 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) antibodyGDNF 适用: 人 WB, IHC, ELISA, IP, FACS 宿主: 兔 Monoclonal 11D2 unconjugated Recombinant Antibody
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 142-158), (Middle Region) antibodyGDNF 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 8-36) antibodyGDNF 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 109-211) antibodyGDNF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 192-207), (Mature) antibodyGDNF 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 121-211) antibody (FITC)GDNF 适用: 人, 小鼠, 大鼠, Cow, 兔 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) antibodyGDNF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 78-211) antibodyGDNF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glial Cell Line Derived Neurotrophic Factor (GDNF) (AA 79-217) antibodyGDNF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 0.5 μg/mL
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说明
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Anti-GDNF is tested for Immunohistochemistry -P and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~23.7 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
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别名
- GDNF
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背景
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Synonyms: Astrocyte-derived trophic factor,
Background: GDNF, Glial cell-derived neurotrophic factor, is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small protein that potently promotes the survival of many types of neurons. GDNF is a founding member of the GDNF family of ligands (GFL).The GDNF gene is mapped to human chromosome 5p13.1-p12 by fluorescence in situ hybridization (FISH). This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosisof motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. This antibody is suitable for researchers interested in neuroscience research.
Gene Name: GDNF
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基因ID
- 2668
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NCBI登录号
- NP_000505
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UniProt
- P39905
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途径
- RTK signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
抗原
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