CYBB 抗体 (Internal Region)
Quick Overview for CYBB 抗体 (Internal Region) (ABIN6657508)
抗原
See all CYBB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 600-401-r16
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Supplier
- Rockland
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原理
- NOX2 Antibody
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交叉反应 （详细）
- Anti-NOX2 antibody is directed against human NOX2 protein.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- NOX2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human NOX2.
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亚型
- IgG
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anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 501-570) antibody
CYBB 适用: 人, 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 283-570) antibodyCYBB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 283-570) antibodyCYBB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (C-Term) antibodyCYBB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) antibodyCYBB 适用: 人 WB, IF, IHC (p), ICC 宿主: 小鼠 Monoclonal 54-1 unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 442-459), (Middle Region) antibodyCYBB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 283-570) antibodyCYBB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (Internal Region) antibodyVerified CYBB 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 100-200) antibodyCYBB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, beta Polypeptide (CYBB) (AA 416-500) antibodyCYBB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:100-1:500
Western_Blot_Dilution: 0.5 μg/mL
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说明
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Anti-NOX2 is tested in Immunohistochemistry -P and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~65.3 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CYBB (Cytochrome B-245, beta Polypeptide (CYBB))
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别名
- NOX2
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背景
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Synonyms: CGD91-phox,Cytochrome b(558) subunit beta,
Background: NOX2(NADPH OXIDASE 2), also called CYBB(CYTOCHROME b(-245), BETA SUBUNIT), p91-PHOX or GP91-1, is a human gene encoding a glycoprotein.NOX2 is an essential component of phagocytic NADPH-oxidase, a membrane-bound enzyme complex that generates large quantities of microbicidal superoxide and other oxidants upon activation. It is mapped on Xp11.4. NOX2 is a heterodimer composed of an alpha chain of relative molecular mass 23 kD and a beta chain of 76 to 82 kD. NOX2 assembled on DC phagosomes in a gp91-phox subunit-dependent manner, and that reactive oxygen species were produced in a more sustained manner in immature DC phagosomes than in macrophage phagosomes .As a major player in innate immune responses in neutrophils,NOX2 is also involved in adaptive immunity through its activity in DCs. In heart cells, physiologic stretch rapidly activates reduced-form NOX2 to produce reactive oxygen species (ROS) in a process dependent on microtubules (X-ROS signaling). This antibody is suitable for researchers interested in cancer research.
Gene Name: CYBB
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基因ID
- 1536
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NCBI登录号
- NP_000388
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UniProt
- P04839
抗原
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