HDAC2 抗体 (pSer394)
Quick Overview for HDAC2 抗体 (pSer394) (ABIN6657454)
抗原
See all HDAC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer394
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Supplier Product No.
- 600-401-x11
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Supplier
- Rockland
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原理
- HDAC2 Phospho S394 Antibody
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交叉反应 (详细)
- Anti-Phospho-Ser394 HDAC2 Antibody is directed against HDAC2 protein phosphorylated at S394.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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过滤
- Sterile filtered
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免疫原
- Anti-Phospho-Ser394 HDAC2 Antibody was produced in rabbits by repeated immunizations with a phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser394 of human HDAC2.
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亚型
- IgG
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Phospho-Ser394 HDAC2 Antibody has been tested by Western Blots and is specific for the ~55 kDa HDAC2 protein phosphorylated at Ser394 in Western blots. Immunolabeling is completely blocked by lambda-Phosphatase treatment (30 minutes, 800units/1mg protein). Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
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有效期
- 12 months
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- HDAC2 (Histone Deacetylase 2 (HDAC2))
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别名
- HDAC2
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背景
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Synonyms: Histone Deacetylase 2, HD2
Background: Histone Deacetylase 2 (HDAC2) is part of a family of histone deacetylases that are responsible for deacetylation of lysine residues in the histone core. HDAC2 is classified as a class I histone deacetylase and is ubiquitously expressed throughout the body. It has been shown that HDAC2 plays an important role in cardiac hypertrophy. Phosphorylation of ser394 is responsible for the hypertrophy-associated activation of HDAC2, whereas intrinsic basal activity is maintained by phosphorylation of ser422 and ser424. HDAC2 pS394 Antibody is ideal for researchers interested in neuroscience research.
Gene Name: HDAC2
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基因ID
- 3066
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NCBI登录号
- NP_001518
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UniProt
- Q92769
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途径
- Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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