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COBRA1 抗体

This 小鼠 单克隆 anti-COBRA1 antibody (Clone F7E4) specifically detects COBRA1 in WB 和 ELISA. The antibody is reactive with 人 samples.
Rockland
产品编号 ABIN6657338
Supplier Product No.: 200-301-d18
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for COBRA1 抗体 (ABIN6657338)

抗原

See all COBRA1 抗体
COBRA1 (Cofactor of BRCA1 (COBRA1))

适用

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宿主

  • 41
  • 5
小鼠

克隆类型

  • 41
  • 5
单克隆

标记

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  • 1
This COBRA1 antibody is un-conjugated

应用范围

  • 35
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Western Blotting (WB), ELISA

克隆位点

F7E4
  • Supplier Product No.

    200-301-d18

    Supplier

    Rockland

    原理

    COBRA 1 Antibody

    交叉反应 (详细)

    This antibody is directed against human COBRA 1.

    纯化方法

    Anti-COBRA 1 antibody was Protein G purified from culture supernatant.

    免疫原

    Anti-COBRA1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant full length human COBRA1 purified from E.coli.

    亚型

    IgG1
  • 应用备注

    ELISA_Dilution: 1:10,000

    Western_Blot_Dilution: 1:1000

    说明

    Anti-COBRA 1 antibody has been tested by ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 62 kDa in size corresponding to COBRA1 proteins in neonatal rat brain lysate or other appropriate lysates.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    COBRA1 (Cofactor of BRCA1 (COBRA1))

    别名

    COBRA 1

    背景

    Synonyms: COBRA1, Negative elongation factor B, NELF-B, Cofactor of BRCA1

    Background: COBRA 1 antibody reacts with COBRA1 (cofactor of BRCA1) also known as NELF-B, which is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription. COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis. Anti-COBRA 1 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

    Gene Name: COBRA1

    基因ID

    25920

    UniProt

    Q8WX92
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