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WASF1 抗体 (C-Term)

WASF1 适用: 人 WB, IHC, FM, IP 宿主: 小鼠 Monoclonal S91-36 unconjugated
Rockland
产品编号 ABIN6656415
Supplier Product No.: 200-301-g64
发货至: 中国
  • 抗原 See all WASF1 抗体
    WASF1 (WAS Protein Family, Member 1 (WASF1))
    抗原表位
    • 15
    • 13
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 44
    • 19
    • 9
    • 1
    • 1
    宿主
    • 43
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 44
    • 4
    单克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WASF1 antibody is un-conjugated
    应用范围
    • 36
    • 20
    • 17
    • 13
    • 13
    • 9
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM), Immunoprecipitation (IP)
    Supplier Product No.
    200-301-g64
    Supplier
    Rockland
    原理
    WAVE1-Scar Antibody
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross-reactivity with WAVE1-Scar from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.
    纯化方法
    Anti-WAVE1-Scar Antibody was purified by Protein G chromatography.
    过滤
    Sterile filtered
    免疫原
    WAVE1-Scar Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to the near c-terminal region of human Wave1/Wasp family1.
    克隆位点
    S91-36
    亚型
    IgG1
    Top Product
    Discover our top product WASF1 Primary Antibody
  • 应用备注

    Immunoprecipitation_Dilution: User Optimized

    Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

    IF_Microscopy_Dilution: 1.0-10 μg/mL

    Western_Blot_Dilution: 1 μg/mL

    说明

    Anti-WAVE1-Scar Antibody is suitable for use in WB, IHC and IP. Expect a band approximately 75kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.09 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    WASF1 (WAS Protein Family, Member 1 (WASF1))
    别名
    WAVE1-Scar (WASF1 产品)
    背景

    Synonyms: Wave1, Scar1, WASP, Wave, WASF1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Verprolin homology domain-containing protein 1

    Background: The Wiskott-Aldrich syndrome protein (WASP) family plays essential roles in the regulation of actin polymerization. There are five WASP family members: Wasp, N-WASP, Wave1 (WASP family verprolin-homologous protein 1), WAVE2 and WAVE3. The Wasp family proteins share a conserved C-terminal region called the verprolin homology, cofilin homology and acidic domain. The Wave/Scar family of prtoteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterized as major regulators of lamellipodia formation downstream of Rac activation, and as members of large protein complexes. IT has been found that all three Scar/Wave isoforms behave similarily and are likely to participate in the same kinds of protein complexes.

    Gene Name: WASF1

    基因ID
    8936
    NCBI登录号
    NP_001020105
    UniProt
    Q92558
    途径
    RTK signaling, Regulation of Actin Filament Polymerization
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