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WASF1 抗体 (AA 91-140)

The 兔 多克隆 anti-WASF1 antibody is suitable to detect WASF1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1532430
发货至: 中国
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Quick Overview for WASF1 抗体 (AA 91-140) (ABIN1532430)

抗原

See all WASF1 抗体
WASF1 (WAS Protein Family, Member 1 (WASF1))

适用

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人, 小鼠, 大鼠

宿主

  • 45
  • 7
  • 1
兔

克隆类型

  • 44
  • 9
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
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This WASF1 antibody is un-conjugated

应用范围

  • 35
  • 23
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  • 13
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  • 7
  • 4
  • 3
  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 15
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 91-140

    原理

    WAVE1 Antibody

    特异性

    WAVE1 Polyclonal Antibody detects endogenous levels of WAVE1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human WAVE1. AA range:91-140

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    WASF1 (WAS Protein Family, Member 1 (WASF1))

    别名

    WAVE1

    背景

    Synonyms: WASF1, KIAA0269, SCAR1, WAVE1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Protein WAVE-1, Verprolin homology domain-containing protein 1

    Background: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

    Gene Name: WASF1

    Protein Name: Wiskott-Aldrich syndrome protein family member 1

    分子量

    61 kDa

    基因ID

    8936

    OMIM

    605035

    UniProt

    Q92558

    途径

    RTK signaling, Regulation of Actin Filament Polymerization
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