SETD8 抗体
Quick Overview for SETD8 抗体 (ABIN6655982)
抗原
See all SETD8 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 100-401-v82
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Supplier
- Rockland
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原理
- SETD8 Antibody
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交叉反应 (详细)
- Cross reactivity with SETD8 from species other than human and mouse not tested.
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纯化方法
- Anti-SETD8 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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过滤
- Sterile filtered
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免疫原
- Anti-SETD8 Antibody was produced in rabbits by repeated immunizations of the full length human SETD8 protein containing a Flag-tagged N-terminus and a His-tagged C terminus.
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亚型
- IgG
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应用备注
- Optional[Neutralization_Dilution]: 1:1,000
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说明
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Anti-SETD8 Antibody has been tested by western blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 40 kDa in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
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别名
- SETD8
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背景
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Synonyms: N-lysine methyltransferase SETD8, H4-K20-HMTase SETD8, Histone-lysine N-methyltransferse SETD8, Lysine N-methyltransferase 5A, PR/SET domain-containing protein 07, SET domain-containing protein 8, PR-Set7, PR/SET07
Background: SETD8 is a histone methyl transferase that specifically monomethylates 'Lys-20' of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression and is enriched during mitosis. SETD8 may also play a role in maintaining silet chromatin by preventing the acetylation of the H4 tail. Anti-SETD8 Antibody is ideal for research in Gene Expression, Epigenetics and Chromatin Remodeling.
Gene Name: SETD8
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基因ID
- 387893
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NCBI登录号
- NP_065115
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UniProt
- Q9NQR1
抗原
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