SETD7 抗体
Quick Overview for SETD7 抗体 (ABIN6655577)
抗原
See all SETD7 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 100-401-v83
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Supplier
- Rockland
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原理
- SET9 Antibody
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交叉反应 (详细)
- Cross reactivity with Set8 from species other than human not tested.
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纯化方法
- Anti-Set9 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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过滤
- Sterile filtered
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免疫原
- Anti-SET9 Antibody was produced in rabbits by repeated immunizations with a recombinant protein of human Set9.
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亚型
- IgG
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应用备注
- Optional[Neutralization_Dilution]: 1:1,000
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说明
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Anti-SET9 Antibody has been tested by Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 50 kDa in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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别名
- Set9
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背景
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Synonyms: Histone-lysine N-methyltransferase SETD7, Histone H3-K4 methyltransferase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET 7/9, H3-K4-HMTase SETD7
Background: Set9 is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deactylation of H3 by the NuRD complex and impairs Suv39h1-mediated methylation of H3K9. Set9 also methylates the tumor suppressor p53 at lysine 372, thereby enchancing its stability. IT contains a SET domain but lacks the pre- and post-SET domains. Anti-Set9 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling.
Gene Name: SETD7
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基因ID
- 80854
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NCBI登录号
- NP_085151
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UniProt
- Q8WTS6
抗原
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