Beclin 1 抗体 (pSer295)
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北京 101111
Quick Overview for Beclin 1 抗体 (pSer295) (ABIN6655420)
抗原
See all Beclin 1 (BECN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer295
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Supplier Product No.
- 600-401-w97
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Supplier
- Rockland
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原理
- BECLIN1 phospho S295 Antibody
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交叉反应 （详细）
- Anti-Phospho-Ser295 Beclin-1 Antibody is directed against Beclin 1 protein phosphorylated at S234.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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过滤
- Sterile filtered
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免疫原
- Anti-Phospho-Ser295 Beclin-1 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser295 of human Beclin-1 conjugated to KLH.
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亚型
- IgG
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anti-Beclin 1, Autophagy Related (BECN1) (AA 201-330) antibody
BECN1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB7463 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-273) antibodyBECN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:2,500
Western_Blot_Dilution: 1:250
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说明
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Anti-Phospho-Ser295 Beclin-1 Antibody is tested for WB. Expect a band at approximately ~60 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user. Immunolabeling of the Beclin-1 band is decreased in the Beclin-1 alanine substitution mutant.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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有效期
- 12 months
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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别名
- Beclin1
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背景
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Synonyms: Run domain Beclin-1 interacting and cysteine-rich containing protein, Rubicon, Beclin-1 associated RUN domain containing protein
Background: Beclin-1 plays a key role in tumor suppression and autophagy. It has been suggested that autophagy proteins such as beclin-1 can inhibit tumorigenesis and that decreased expression of these proteins may contribute to the development of human malignancies. Beclin-1 has been shown to interact with 14-3-3 proteins through Akt-mediated phosphorylation at Ser234. Beclin 1 pS295 Antibody is ideal for researchers interested in cancer research.
Gene Name: BECN1
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基因ID
- 8678
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NCBI登录号
- NP_001300927
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UniProt
- Q14457
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途径
- Autophagy
抗原
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