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BIRC7 抗体

This anti-BIRC7 antibody is a 小鼠 单克隆 antibody detecting BIRC7 in WB, IF 和 FM. Suitable for 人.
Rockland
产品编号 ABIN6655300
Supplier Product No.: 200-301-h90
发货至: 中国

Quick Overview for BIRC7 抗体 (ABIN6655300)

抗原

See all BIRC7 抗体
BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This BIRC7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Fluorescence Microscopy (FM)

克隆位点

88C570
  • Supplier Product No.

    200-301-h90

    Supplier

    Rockland

    原理

    Livin Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with Livin from human based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-Livin Antibody was purified by Protein G chromatography.

    免疫原

    Livin Antibody was produced in mice prepared by repeated immunizations with recombinant human protein, Livin.

    亚型

    IgG1 kappa
  • 应用备注

    IF_Microscopy_Dilution: 2-5 μg/mL

    Western_Blot_Dilution: 1-2 μg/mL

    说明

    Anti-Livin antibody is tested for use in IF/ICC and WB. Expect a band approximately 30kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

    别名

    Livin

    背景

    Synonyms: KIAP, LIVIN, MLIAP, RNF50, BIRC7, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50

    Background: Anti-Livin BIRC7 KIAP antibody detects human Livin BIRC7 KIAP. The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently a novel human inhibitor of apoptosis protein (IAP) family member termed Livin or ML-IAP, which contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain, has been identified. Livin gene has two splicing variants that contain open reading frames of 298 and 280 amino acids and both contained a single copy of baculovirus IAP repeat (BIR) and RING domain. Both of the isoforms inhibit TNFa induced apoptosis in Jurkat cells. Livin expression is low in adult tissues. It is relatively expressed at a higher level in developmental tissues and in many cancer cells. Anti-Livin BIRC7 KIAP antibody is ideal for investigators invovled in apoptosis reasearch.

    Gene Name: BIRC7

    基因ID

    79444

    NCBI登录号

    NP_071444

    UniProt

    Q96CA5
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