PRMT6 抗体
Quick Overview for PRMT6 抗体 (ABIN6655272)
抗原
See all PRMT6 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 100-401-i04
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Supplier
- Rockland
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原理
- PRMT6 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with PRMT6 from human and mouse based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-PRMT6 Antibody is sera.
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免疫原
- PRMT6 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to internal amino acids of human PRMT6 protein.
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亚型
- IgG
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anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibody
PRMT6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 19-48) antibodyPRMT6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 119-375) antibodyPRMT6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibodyPRMT6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 1-316) antibodyPRMT6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) antibodyPRMT6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (AA 301-375) antibodyPRMT6 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (Internal Region) antibodyVerified PRMT6 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (C-Term) antibodyPRMT6 适用: 人, 大鼠, 犬, 马, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 6 (PRMT6) (N-Term) antibodyPRMT6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1:100-1:1000
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说明
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Anti-PRMT6 is tested for use in WB. Expect a band approximately 42kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
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别名
- PRMT6
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背景
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Synonyms: HRMT1L6, Protein arginine N-methyltransferase 6, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6
Background: Anti-PRMT6 Antibody detects human PRMT6. Protein arginine methylation is an important posttranslational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT6 was identified by searching the human genome for protein arginine N-methyltransferase (PRMT) family members. PRMT6 cDNA codes for a protein of approximate molecular weight of 42 kDa consisting of a catalytic core sequence common to other PRMT enzymes. PRMT6 demonstrates type I PRMT activity, capable of forming both >NG-monomethylarginine and asymmetric >NG,NG-dimethylarginine derivatives on the recombinant glycine- and arginine-rich substrates. A comparison of substrate specificity reveals that PRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition to methylating substrate proteins, PRMT6 displays automethylation activit. GFP-fusion protein expression in the transfected cell lines suggest that PRMT6 localizes in the nucleus. Anti-PRM6 is ideal for researchers interested in NFkappaB research.
Gene Name: PRMT6
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基因ID
- 55170
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NCBI登录号
- NP_060607
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UniProt
- Q96LA8
抗原
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