L-Selectin 抗体 (PE)
Quick Overview for L-Selectin 抗体 (PE) (ABIN6655168)
抗原
See all L-Selectin (SELL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-308-n72
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Supplier
- Rockland
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原理
- CD62L Phycoerythrin Antibody
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交叉反应 (详细)
- Reactivity is observed against human CD62L.
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纯化方法
- Phycoerythrin conjugated CD62L Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD62L.
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过滤
- Sterile filtered
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免疫原
- Anti-CD62L Antibody (Monoclonal) was produced by repeated immunizations with CD62L antigen.
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亚型
- IgG1 kappa
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Labeling Ratio
- 1-2
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应用备注
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Flow_Cytometry_Dilution: 5 uL/test/1x10e5 to 1x10e8 cells
Western_Blot_Dilution: User Optimized
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说明
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Anti-CD62L is tested for Flow Cytometry and useful in Western Blot. Researchers should determine optimal titers for applications that are not stated.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.2 % BSA (w/v)
Preservative: 0.09 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
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有效期
- 6 months
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- L-Selectin (SELL) (Selectin L (SELL))
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别名
- CD62L
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背景
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Synonyms: L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, TQ1, gp90-MEL, CD62L , SELL , LNHR, LYAM1
Background: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Gene Name: SELL
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基因ID
- 6402
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NCBI登录号
- NP_000646
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UniProt
- P14151
抗原
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