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CD25 抗体 (PE)

This anti-CD25 antibody is a 小鼠 单克隆 antibody detecting CD25 in FACS. Suitable for 人.
Rockland
产品编号 ABIN6655113
Supplier Product No.: 200-308-n25
发货至: 中国

Quick Overview for CD25 抗体 (PE) (ABIN6655113)

抗原

See all CD25 (IL2RA) 抗体
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD25 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

BC96
  • Supplier Product No.

    200-308-n25

    Supplier

    Rockland

    原理

    CD25 Phycoerythrin Antibody

    交叉反应 (详细)

    Reactivity is observed against human CD25, Baboon, Chimpanzee, Cynomolgus, and Rhesus.

    纯化方法

    Phycoerythrin conjugated CD25 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD25.

    过滤

    Sterile filtered

    免疫原

    Anti-CD25 Antibody (Monoclonal) was produced by repeated immunizations with CD25 antigen.

    亚型

    IgG1 kappa

    Labeling Ratio

    1-2
  • 应用备注

    Optional[Neutralization_Dilution]: 5μL/test/1x10e5 to 1x10e8 cells

    说明

    Anti-CD25 is tested for Flow Cytometry. Researchers should determine optimal titers for applications that are not stated.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    Preservative: 0.09 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

    有效期

    6 months
  • 抗原

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    别名

    CD25

    背景

    Synonyms: Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55

    Background: The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells. The BC96 antibody may be used as a marker for expression of CD25 during T and B cell development, on activated mature T and B cells, and for its expression at high levels on natural T regulatory cells (nTreg cells) in the thymus or periphery, and on induced peripheral Tregs.

    Gene Name: IL2RA

    基因ID

    3559

    NCBI登录号

    NP_000408

    UniProt

    P01589

    途径

    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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