CD40 Ligand 抗体 (PE)
Quick Overview for CD40 Ligand 抗体 (PE) (ABIN6655108)
抗原
See all CD40 Ligand (CD40LG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-308-n76
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Supplier
- Rockland
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原理
- CD154 (CD40L) Phycoerythrin Antibody
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交叉反应 (详细)
- Reactivity is observed against human CD154.
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纯化方法
- Phycoerythrin conjugated CD154 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD154.
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过滤
- Sterile filtered
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免疫原
- Anti-CD154 Antibody (Monoclonal) was produced by repeated immunizations with CD154 antigen.
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亚型
- IgG1 kappa
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Labeling Ratio
- 1-2
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应用备注
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Flow_Cytometry_Dilution: 5 uL/test/1x10e5 to 1x10e8 cells
IF_Microscopy_Dilution: User Optimized
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说明
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Anti-CD154 is tested for Flow Cytometry and useful in Immunofluorescence. Researchers should determine optimal titers for applications that are not stated.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.2 % BSA (w/v)
Preservative: 0.09 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
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有效期
- 6 months
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- CD40 Ligand (CD40LG)
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别名
- CD154 (CD40L)
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背景
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Synonyms: CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD40LG, CD40L, TNFSF5, TRAP
Background: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
Gene Name: CD40LG
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基因ID
- 959
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NCBI登录号
- NP_000065
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UniProt
- P29965
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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