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Cyclin L1 抗体 (AA 314-369)

This anti-Cyclin L1 antibody is a 兔 多克隆 antibody detecting Cyclin L1 in WB, IHC, ELISA 和 IP. Suitable for 人. This Primary Antibody has been cited in 1 publication.
Rockland
产品编号 ABIN6655105
Supplier Product No.: 200-401-881
发货至: 中国

Quick Overview for Cyclin L1 抗体 (AA 314-369) (ABIN6655105)

抗原

See all Cyclin L1 (CCNL1) 抗体
Cyclin L1 (CCNL1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cyclin L1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 抗原表位

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    AA 314-369

    Supplier Product No.

    200-401-881

    Supplier

    Rockland

    原理

    Cyclin L1 Antibody

    交叉反应 (详细)

    This antibody is specific for human Cyclin L1a and shows negligible reactivity to Cyclin L1b or Cyclin L2 isoforms.

    纯化方法

    The product was purified from monospecific antiserum by Protein A chromatography.

    免疫原

    This Protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic polypeptide corresponding to an internal region near amino acids 300-375 of Human Cyclin L1a protein.

    亚型

    IgG
  • 应用备注

    Immunoprecipitation_Dilution: 1:100

    ELISA_Dilution: 1:5,000 - 1:25,000

    Immunohistochemistry_Dilution: 10 mg/mL - 20 μg/mL

    Western_Blot_Dilution: 1:2,000 - 1:5,000

    Other: User Optimized

    说明

    This Protein A purified antibody has been tested for use in ELISA, immunohistochemistry, western blot, and immunoprecipitation.   Specific conditions for reactivity should be optimized by the end user.  Expect a band ~ 59 kDa in size corresponding to Cyclin L1a by western blotting in the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 100 μL

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at 4° C prior to restoration.   For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use. 

    有效期

    12 months
  • Loyer, Trembley, Katona, Kidd, Lahti: "Role of CDK/cyclin complexes in transcription and RNA splicing." in: Cellular signalling, Vol. 17, Issue 9, pp. 1033-51, (2005) (PubMed).

  • 抗原

    Cyclin L1 (CCNL1)

    别名

    Cyclin L1

    背景

    Synonyms: rabbit anti-Cyclin L1 antibody, Cyclin-L, Cyclin L beta, Cyclin L gamma, CCNL1

    Background: Cyclin L (also referred to as CCNL) is encoded by two highly related genes Cyclin L1 and Cyclin L2 (CCNL1 and CCNL2, respectively). Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. Both Cyclin L gene products can be alternatively spliced to produce two isoforms (known as 1 and 2 or alpha and beta). Cyclin L2 is ubiquitous, expressed at much higher levels than Cyclin L1, and thus is likely the major partner for the CDK11p110 protein kinase.

    Gene Name: CCNL1

    基因ID

    57018

    NCBI登录号

    NP_064703

    UniProt

    Q9UK58
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