Cyclin L1 抗体 (AA 461-510)
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Quick Overview for Cyclin L1 抗体 (AA 461-510) (ABIN1533373)
抗原
See all Cyclin L1 (CCNL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 461-510
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原理
- Cyclin L1 Antibody
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特异性
- Cyclin L1 Polyclonal Antibody detects endogenous levels of Cyclin L1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Cyclin L1. AA range:461-510
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亚型
- IgG
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anti-Cyclin L1 (CCNL1) (AA 1-172) antibody
CCNL1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F7-1C5 unconjugated
anti-Cyclin L1 (CCNL1) (C-Term) antibodyCCNL1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) antibodyCCNL1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 314-369) antibodyCCNL1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 350-400) antibodyCCNL1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 32-81) antibodyCCNL1 适用: 人, 大鼠, 小鼠, Cow, Pig, 豚鼠, 非洲爪蟾, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (C-Term) antibodyCCNL1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 350-400) antibodyCCNL1 适用: 人 IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 300-350) antibodyCCNL1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 430-510) antibodyCCNL1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cyclin L1 (CCNL1)
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别名
- Cyclin L1
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背景
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Synonyms: CCNL1, BM-001, Cyclin-L1, Cyclin-L
Background: alternative products:Ccnl1 is an immediate-early gene with independently regulated isoforms,domain:Contains a RS region (arginine-serine dipeptide repeat) within the C-terminal domain which is the hallmark of the SR family of splicing factors. This region probably plays a role in protein-protein interactions.,function:Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.,miscellaneous:CCNL1 is amplified in several HNSCC. May play a critical role in the formation of loco-regional metastases and an unfavorable clinical outcome of HNSCC.,sequence caution:Probable cloning artifact.,similarity:Belongs to the cyclin family. Cyclin L subfamily.,subcellular location:More specifically found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.,subunit:Interacts with POLR2A via its hyperphosphorylated C-terminal domain (CTD) (By similarity). Interacts with CDC2L1 or CDC2L2, and SFRS2.,tissue specificity:Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).,
Gene Name: CCNL1
Protein Name: Cyclin-L1
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分子量
- 59 kDa
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基因ID
- 57018
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UniProt
- Q9UK58
抗原
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