Cyclin L1 抗体 (AA 314-369)
(1 reference)-
- 抗原 See all Cyclin L1 (CCNL1) 抗体
- Cyclin L1 (CCNL1)
-
抗原表位
- AA 314-369
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Cyclin L1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
- 交叉反应 （详细）
- Cross reactivity with Cyclin L1a protein from dog, rat, mouse and chicken is expected, as this sequence shows 87-96 % homology with the protein from these sourcesCross reactivity with Cyclin L1a homologues from other sources has not been determined.
- 纯化方法
- The product was purified from monospecific antiserum by Protein A chromatography. This antibody is specific for human Cyclin L1a and shows negligible reactivity to Cyclin L1b or Cyclin L2 isoforms. A BLAST analysis was used to suggest reactivity with this protein from human and chimpanzee based on 100% homology for the immunogen sequence. Cross reactivity with Cyclin L1a protein from dog, rat, mouse and chicken is expected, as this sequence shows 87-96% homology with the protein from these sources. Cross reactivity with Cyclin L1a homologues from other sources has not been determined.
- 免疫原
-
Immunogen: This Protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic polypeptide corresponding to amino acids 314-369 of Human Cyclin L1a protein.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product CCNL1 Primary Antibody
-
anti-Cyclin L1 (CCNL1) (C-Term) antibody
CCNL1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 1-172) antibodyCCNL1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F7-1C5 unconjugated
anti-Cyclin L1 (CCNL1) (C-Term) antibodyCCNL1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (C-Term) antibodyCCNL1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 32-81) antibodyCCNL1 适用: 人, 大鼠, 小鼠, Cow, Pig, 豚鼠, 非洲爪蟾, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (C-Term) antibodyCCNL1 适用: 人, 大鼠, 小鼠, 犬, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin L1 (CCNL1) (AA 461-510) antibodyCCNL1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Immunohistochemistry Dilution: 10 mg/mL - 20 μg/mL
Application Note: This Protein A purified antibody has been tested for use in ELISA, immunohistochemistry, western blot, and immunoprecipitation. Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 59 kDa in size corresponding to Cyclin L1a by western blotting in the appropriate cell lysate or extract.
Immunoprecipitation Dilution: 1:100
ELISA Dilution: 1:5,000 - 1:25,000
Western Blot Dilution: 1:2,000 - 1:5,000
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
-
Reconstitution Volume: 100 μL
Reconstitution Buffer: Restore with deionized water (or equivalent)
- 缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
0.01 % (w/v) Sodium AzideStabilizer: None
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
-
: "Role of CDK/cyclin complexes in transcription and RNA splicing." in: Cellular signalling, Vol. 17, Issue 9, pp. 1033-51, (2005) (PubMed).
-
: "Role of CDK/cyclin complexes in transcription and RNA splicing." in: Cellular signalling, Vol. 17, Issue 9, pp. 1033-51, (2005) (PubMed).
-
- 抗原
- Cyclin L1 (CCNL1)
- 别名
- Cyclin L1 (CCNL1 产品)
- 别名
- ANIA6A antibody, PRO1073 antibody, ania-6a antibody, 2610030E23Rik antibody, AU018493 antibody, Ccnl antibody, Ania-6a antibody, ccnl1 antibody, fd99b09 antibody, wu:fd99b09 antibody, zgc:55544 antibody, MCM2 antibody, cyclin-L1 antibody, MGC132032 antibody, bm-001 antibody, pro1073 antibody, MGC108436 antibody, Ccnl1 antibody, cyclin L1 antibody, cyclin L1b antibody, cyclin-L1 antibody, cyclin L1 L homeolog antibody, cyclin L1 S homeolog antibody, CCNL1 antibody, Ccnl1 antibody, ccnl1b antibody, LOC485730 antibody, ccnl1.L antibody, ccnl1 antibody, LOC100136245 antibody, ccnl1.S antibody
- 背景
-
Synonyms: rabbit anti-Cyclin L1 antibody, Cyclin-L, Cyclin L beta, Cyclin L gamma, CCNL1
Background: Cyclin L (also referred to as CCNL) is encoded by two highly related genes Cyclin L1 and Cyclin L2 (CCNL1 and CCNL2, respectively). Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. Both Cyclin L gene products can be alternatively spliced to produce two isoforms (known as 1 and 2 or alpha and beta). Cyclin L2 is ubiquitous, expressed at much higher levels than Cyclin L1, and thus is likely the major partner for the CDK11p110 protein kinase.
Gene Name: CCNL1
- 基因ID
- 57018
- NCBI登录号
- NP_064703
- UniProt
- Q9UK58
-
