p63 抗体
Quick Overview for p63 抗体 (ABIN6655001)
抗原
See all p63 (TP63) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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纯度
- Protein G affinity chromatography
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免疫原
- Full length human recombinant protein was used as the immunogen for the p63 antibody.
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亚型
- IgG2a
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anti-Tumor Protein P63 (TP63) antibody
KO Validated TP63 适用: 人 WB, ICC, IF, IP, IHC (p), IHC (fro), PLA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 421-680) antibodyTP63 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (AA 5-17) antibodyTP63 适用: 人, 小鼠, 大鼠, Cow WB, IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TP63-2428 unconjugated
anti-Tumor Protein P63 (TP63) (AA 3-106) antibodyTP63 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TP63-1786 unconjugated
anti-Tumor Protein P63 (TP63) (AA 664-680), (C-Term) antibodyTP63 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠 IHC, StM 宿主: 小鼠 Monoclonal TP63-11 unconjugated
anti-Tumor Protein P63 (TP63) (C-Term) antibodyTP63 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) antibodyTP63 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P63 (TP63) (pSer455) antibodyTP63 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Optimal dilution of the p63 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1) -
限制
- 仅限研究用
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the p63 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- p63 (TP63) (Tumor Protein P63 (TP63))
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别名
- p63 / Tumor protein 63
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背景
- P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
抗原
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